![]() In addition, this study derived MMSE, MoCA, and ADAS-cog norms tailored to demographic factors. The Taiwan version of ADAS-cog is compatible with MMSE and MoCA to distinguish people with mildly impaired from normal cognition. Discussion/Conclusion: The three structured cognitive tests consistently reflect cognitive levels of healthy older adults. In addition, ADAS-cog discriminated CDR 0.5 from 0 by an AUROC of 0.827 ( p < 0.001). Next, in the 170 mixed participants from the communities and the hospital, MMSE, MoCA, and ADAS-cog scores were well differentiable between CDR 0, 0.5, and 1. The normative data of MMSE, MoCA, and ADAS-cog showed ladder changes with age ( p = 0.006, 0.001, and 0.437) and education ( p < 0.001, <0.001, and <0.001) in the 150 nondemented older adults. Results: The Taiwan version of ADAS-cog had fair reliability between items (α = 0.727) and good correlations to MMSE ( r = −0.673, p < 0.001) and MoCA ( r = −0.746, p < 0.001). The area under the receiver operating characteristic curve (AUROC) analyzed the power of ADAS-cog in predicting CDR 0.5 from CDR 0. Comparisons in the Clinical Dementia Rating (CDR) tiers tested the discriminability of the tests for different cognitive levels. Another 20 hospital-acquired participants with cognitive impairment joined the 150 healthy participants. Normative data were generated and stratified by age and education, and the one-way analysis of variance compared scores between age and education groups. Cronbach’s alpha (α) tested the reliability of ADAS-cog, and Pearson correlations examined its external validity using MMSE and MoCA as comparisons. ADAS-cog was translated from the original English version to traditional Chinese with cultural and language considerations in Taiwan. Methods: MMSE, MoCA, and ADAS-cog were administered to 150 nondemented healthy adults aged 55–85 years during 2018–2020 as part of the Northeastern Taiwan Community Medicine Research Cohort. This study validated the Taiwan version of the Alzheimer’s Disease Assessment Scale-Cognitive subscale (ADAS-cog) and provided normative data for the Mini-Mental State Examination (MMSE), the Montreal Cognitive Assessment (MoCA), and ADAS-cog in community-dwelling older adults. Introduction: Appropriate tools and references are essential for evaluating individuals’ cognitive levels.
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